Multifunctional oligomer incorporation: a potent strategy to enhance the transfection activity of poly(l-lysine)

Author:

Liu Shuai12345,Yang Jixiang12345,Ren Hongqi12345,O'Keeffe-Ahern Jonathan6789,Zhou Dezhong6789,Zhou Hao101151213,Chen Jiatong101151213,Guo Tianying12345

Affiliation:

1. Key Laboratory of Functional Polymer Materials

2. Ministry of Education

3. Institute of Polymer Chemistry

4. College of Chemistry

5. Nankai University

6. Charles Institute of Dermotology

7. University College Dublin

8. Dublin 4

9. Ireland

10. Department of Biochemistry and Molecular Biology

11. College of Life Science

12. Tianjin 300071

13. China

Abstract

The multifunctional oligomer incorporation strategy is used for the first time to evaluate target effects by the ligand modified oligomer assembly, forming complexes with DNA and polycations.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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