Simultaneous detection of multiple NT-proBNP clinical samples utilizing an aptamer-based sandwich assay on an integrated microfluidic system-Reference-Cited by-同舟云学术

Simultaneous detection of multiple NT-proBNP clinical samples utilizing an aptamer-based sandwich assay on an integrated microfluidic system

Published:2019 Issue:9 Volume:19 Page:1676-1685
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Sinha Anirban¹²³⁴^ORCID,Gopinathan Priya¹²³⁴^ORCID,Chung Yi-Da⁵²⁶⁴,Shiesh Shu-Chu⁷⁸⁹¹⁰⁴,Lee Gwo-Bin¹²³⁴⁵^ORCID

Affiliation:

1. Institute of NanoEngineering and Microsystems

2. National Tsing Hua University

3. Hsinchu

4. Taiwan

5. Department of Power Mechanical Engineering

6. Hsinchu 30013

7. Department of Medical Laboratory Science and Biotechnology

8. College of Medicine

9. National Cheng Kung University

10. Tainan

Abstract

An integrated microfluidic platform was developed for the simultaneous detection of NT-proBNP, a widely studied biomarker for heart failure diagnosis, in up to six clinical samples within 25 min by using a novel aptamer-based sandwich assay.

Funder

Ministry of Science and Technology, Taiwan

Ministry of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/LC/C9LC00115H

Reference42 articles.

1. Global Public Health Burden of Heart Failure

2. Epidemiology and risk profile of heart failure

3. A brief review of biomarkers for preventing and treating cardiovascular diseases

4. Identifying novel biomarkers for cardiovascular disease risk prediction

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