A convenient protonated strategy for constructing nanodrugs from hydrophobic drug-inhibitor conjugates to reverse tumor multidrug resistance-Reference-Cited by-同舟云学术

A convenient protonated strategy for constructing nanodrugs from hydrophobic drug-inhibitor conjugates to reverse tumor multidrug resistance

Published:2024 Issue:17 Volume:16 Page:8434-8446
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Wang Penghui¹,Wang Yuling¹,Xia Xuelin¹,Wu Jingchun²,Lin Jintang²,Huang Wei¹^ORCID,Yan Deyue¹^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China

2. Zhejiang Hopeland Chemical Co., LTD, 26 Luyin Road, Quzhou Hi-Tech Industrial Park, Zhejiang 324100, China

Abstract

A novel nanodrug constructed from hydrophobic drug-inhibitor conjugates through a protonated strategy to synergistically reverse MDR and inhibit tumor growth.

Funder

Shanghai Jiao Tong University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D3NR06293G

Reference57 articles.

1. Self-Assembly of an Amphiphilic Janus Camptothecin-Floxuridine Conjugate into Liposome-Like Nanocapsules for More Efficacious Combination Chemotherapy in Cancer

2. Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multidrug Resistance

3. A Tailored DNA Nanoplatform for Synergistic RNAi‐/Chemotherapy of Multidrug‐Resistant Tumors

4. Engineered celastrol and plasmid co-delivery for in situ expression and targeted mitochondrial relocation of Nur77 protein towards effective drug resistance reversion

5. Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding