Total syntheses of smenothiazoles A and B
Author:
Affiliation:
1. Laboratory of Chemical Genomics
2. Engineering Laboratory for Chiral Drug Synthesis
3. School of Chemical Biology and Biotechnology
4. Peking University Shenzhen Graduate School
5. Shenzhen
Abstract
Stereocontrolled installation of vinyl chloride and the 2,5-diene system via silastannation, Stille reaction and desilylchlorination, and the final peptide coupling reactions led to the concise total synthesis of smenothiazoles A (1) and B (2).
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01818E
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