Facile synthesis of penta-substituted pyrroles and pyrrole-fused piperidin-4-ones via four component reactions of 2,3-diketoesters, anilines and enaminones-Reference-Cited by-同舟云学术

Facile synthesis of penta-substituted pyrroles and pyrrole-fused piperidin-4-ones via four component reactions of 2,3-diketoesters, anilines and enaminones

Published:2021 Issue:20 Volume:8 Page:5716-5721
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yu Tongyan¹,Ji Fei²,Huang Daichuan¹,Gao Ya¹^ORCID,Shi Zhaoping¹,Sha Xuan²,Xu Jiangyan¹,You Siliang³,Zhang Mingzhi¹,Sha Qiang¹^ORCID

Affiliation:

1. Jiangsu Key Laboratory of Pesticide Science and Department of Chemistry, College of Sciences, Nanjing Agricultural University, 1 Weigang Road, Xuanwu District, Nanjing 210095, P. R. China

2. Department of Pharmaceutical Engineering, China Pharmaceutical University, 639 Longmian Avenue, Jiangning District, Nanjing, 211198, P. R. China

3. State Key laboratory of Crop Genetics and Germplasm Enhancement, College of Agriculture, Nanjing Agricultural University, 1 Weigang Road, Xuanwu District, Nanjing 210095, P. R. China

Abstract

Novel and facile multicomponent reactions of 2,3-diketoesters, anilines and enaminones were developed. A variety of penta-substituted pyrroles and pyrrole-fused piperidin-4-ones can be easily accessed via interception of cationic intermediates.

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00921D

Reference47 articles.

1. Chemistry of vicinal polyketones

2. The Chemistry of Vicinal Polycarbonyl Compounds