Digestion of lipid micelles leads to increased membrane permeability-Reference-Cited by-同舟云学术

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Digestion of lipid micelles leads to increased membrane permeability

Published:2024 Issue:5 Volume:16 Page:2642-2653
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Xie Jun¹,Pink Demi L.¹,Jayne Lawrence M.²^ORCID,Lorenz Christian D.¹^ORCID

Affiliation:

1. Biological & Soft Matter Research Group, Department of Physics, Faculty of Natural, Mathematical & Engineering Sciences, King's College London, London, UK

2. Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Stopford Building, Oxford Road, Manchester, UK

Abstract

Our all-atom molecular dynamics simulations characterize the interactions of a short chain lipid and its digestion products with disordered & ordered lipid membranes, and provide a mechanistic understanding of the resulting permeability enhancement.

Funder

Engineering and Physical Sciences Research Council

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D3NR05083A

Reference76 articles.

1. Impact of drug aggregation on the structural and dynamic properties of Triton X-100 micelles

2. The Impact of Lipid Digestion on the Dynamic and Structural Properties of Micelles

3. Interplay of lipid and surfactant: Impact on nanoparticle structure

4. On the Structure of Solid Lipid Nanoparticles

5. Atomistic Description of the Solubilisation of Testosterone Propionate in a Sodium Dodecyl Sulfate Micelle

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