Iodonium ylides for one-step, no-carrier-added radiofluorination of electron rich arenes, exemplified with 4-(([18F]fluorophenoxy)-phenylmethyl)piperidine NET and SERT ligands-Reference-Cited by-同舟云学术

Iodonium ylides for one-step, no-carrier-added radiofluorination of electron rich arenes, exemplified with 4-(([18F]fluorophenoxy)-phenylmethyl)piperidine NET and SERT ligands

Published:2014 Issue:33 Volume:4 Page:17293-17299
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Cardinale Jens¹²³⁴⁵,Ermert Johannes¹²³⁴,Humpert Sven¹²³⁴,Coenen Heinz H.¹²³⁴

Affiliation:

1. Institut für Neurowissenschaften und Medizin

2. INM-5: Nuklearchemie

3. Forschungszentrum Jülich GmbH

4. 52425 Jülich, Germany

5. Department of Medical Physics in Radiology

Abstract

Iodonium ylide precursors of electron rich arenes, i.e. the NET and SERT ligands 4-((3- and 4-fluorophenoxy)phenylmethyl)piperidine, served as model compounds for the direct substitution with n.c.a. [¹⁸F]fluoride.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA00674G

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