Glycosides and flavonoids from the extract of <i>Pueraria thomsonii</i> Benth leaf alleviate type 2 diabetes in high-fat diet plus streptozotocin-induced mice by modulating the gut microbiota-Reference-Cited by-同舟云学术

Glycosides and flavonoids from the extract of Pueraria thomsonii Benth leaf alleviate type 2 diabetes in high-fat diet plus streptozotocin-induced mice by modulating the gut microbiota

Published:2022 Issue:7 Volume:13 Page:3931-3945
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhang Shan-Shan¹²^ORCID,Zhang Niu-Niu²,Guo Sen²,Liu Shao-Jing¹³,Hou Yu-Fei²,Li Shiming⁴,Ho Chi-Tang⁵^ORCID,Bai Nai-Sheng²^ORCID

Affiliation:

1. College of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Shaanxi 710069, China

2. College of Food Science and Technology, Northwest University, 229 Taibai North Road, Shaanxi 710069, China

3. College of Pharmacy, Xi'an Medical University, 1 Xinwang Road, Shaanxi 710021, China

4. College of Life Sciences, Huanggang Normal University, Hubei 438000, China

5. Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey 08901, USA

Abstract

Twenty glycoside derivatives and nine flavonoids from the leaves of Pueraria (P. thomsonii) were isolated by column chromatography and characterized by nuclear magnetic resonance spectroscopy (NMR) and high performance liquid chromatography (HPLC).

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO04170C

Reference66 articles.

1. A practical guide for induction of type-2 diabetes in rat: Incorporating a high-fat diet and streptozotocin

2. Anti-obesity and anti-diabetic effects of nitrate and nitrite

3. Inflammatory links between obesity and metabolic disease

4. Arabinoxylan ameliorates type 2 diabetes by regulating the gut microbiota and metabolites

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