In vivo delivery of nuclear targeted drugs for lung cancer using novel synthesis and functionalization of iron oxide nanocrystals

Author:

Vellingiri Sreevani1,Rejeeth Chandrababu23ORCID,Varukattu Nipun Babu4,Sharma Alok5ORCID,Kumar Raju Suresh6ORCID,Almansour Abdulrahman I.6,Arumugam Natarajan6ORCID,Afewerki Samson78ORCID,Kannan Soundarapandian9

Affiliation:

1. Proteomics and Molecular Cell Physiology Laboratory, Department of Zoology, Bharathiar University, Coimbatore, Tamil Nadu, India

2. School of Biomedical Engineering, Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, P. R. China

3. Department of Biochemistry, Periyar University, Salem, Tamil Nadu 636011, India

4. Cancer Research Center, Shantou University Medical College, Shantou, Guangdong 515041, P. R. China

5. Department of Pharmacognosy ISF College of Pharmacy, Moga, Punjab 142001, India

6. Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia

7. Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA

8. Division of Health Sciences and Technology, Harvard University – Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, USA

9. Division of cancer nanomedicine, School of life science, Periyar University, Salem 636011, India

Abstract

Iron nanoparticles are typically made from inorganic precursors, but for the first time, we synthesized-Fe2O3-NCs from goat blood (a bio-precursor) employing the RBC lysis method (a molecular level approach).

Funder

University Grants Commission

Shanghai Jiao Tong University

King Saud University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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