A highly stable multifunctional aptamer for enhancing antitumor immunity against hepatocellular carcinoma by blocking dual immune checkpoints-Reference-Cited by-同舟云学术

A highly stable multifunctional aptamer for enhancing antitumor immunity against hepatocellular carcinoma by blocking dual immune checkpoints

Published:2021 Issue: Volume: Page:
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Du Yanlin¹²³⁴⁵,Zhang Da¹²³⁴^ORCID,Wang Yiru⁶⁷⁸⁴,Wu Ming¹²³⁴^ORCID,Zhang Cuilin¹²³⁴,Zheng Youshi¹²³⁴,Zheng Aixian¹²³⁴,Liu Xiaolong¹²³⁴⁵^ORCID

Affiliation:

1. The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province

2. Mengchao Hepatobiliary Hospital of Fujian Medical University

3. Fuzhou 350025

4. P. R. China

5. Fujian Institute of Research on The Structure of Matter

6. College of Biological Science and Engineering

7. Fuzhou University

8. Fuzhou 350116

Abstract

A highly stable multifunctional aptamer was prepared for strengthening antitumor immunity through a dual immune checkpoint blockade of CTLA-4 and PD-L1.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Science and Technology Projects of Fujian Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM02210A

Reference42 articles.

1. Challenges of combination therapy with immune checkpoint inhibitors for hepatocellular carcinoma

2. Immune checkpoint inhibition: prospects for prevention and therapy of hepatocellular carcinoma

3. Immunotherapy for hepatocellular carcinoma: Current and future

4. A global view of hepatocellular carcinoma: trends, risk, prevention and management

5. Association Between Expression Level of PD1 by Tumor-Infiltrating CD8+ T Cells and Features of Hepatocellular Carcinoma

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