Water and hydrophobic gates in ion channels and nanopores-Reference-Cited by-同舟云学术

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Water and hydrophobic gates in ion channels and nanopores

Published:2018 Issue: Volume:209 Page:231-247
ISSN:1359-6640
Container-title:Faraday Discussions
language:en
Short-container-title:Faraday Discuss.

Author:

Rao Shanlin¹²³^ORCID,Lynch Charlotte I.¹²³^ORCID,Klesse Gianni¹²³⁴⁵^ORCID,Oakley Georgia E.¹²³^ORCID,Stansfeld Phillip J.¹²³^ORCID,Tucker Stephen J.⁴⁵²³^ORCID,Sansom Mark S. P.¹²³^ORCID

Affiliation:

1. Department of Biochemistry

2. University of Oxford

3. UK

4. Clarendon Laboratory

5. Department of Physics

Abstract

Simulations of water behaviour have been used to probe hydrophobic gates in BEST1 and TMEM175, which can reveal important design principles for the engineering of gates in novel biomimetic nanopores.

Funder

Biotechnology and Biological Sciences Research Council

Engineering and Physical Sciences Research Council

Leverhulme Trust

Wellcome

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/FD/C8FD00013A

Reference56 articles.

1. Cryo-EM: beyond the microscope

2. HOLE: A program for the analysis of the pore dimensions of ion channel structural models

3. A Hydrophobic Gating Mechanism for Nanopores

4. Liquid-vapor oscillations of water in hydrophobic nanopores

5. Not Ions Alone: Barriers to Ion Permeation in Nanopores and Channels

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