Generating linear oxygen gradients across 3D cell cultures with block-layered oxygen controlled chips (BLOCCs)-Reference-Cited by-同舟云学术

Generating linear oxygen gradients across 3D cell cultures with block-layered oxygen controlled chips (BLOCCs)

Published:2020 Issue:1 Volume:12 Page:18-24
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Boyce Matthew W.¹²³⁴⁵,Simke William C.¹²³⁴⁵,Kenney Rachael M.¹²³⁴⁵,Lockett Matthew R.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. University of North Carolina at Chapel Hill

3. Kenan and Caudill Laboratories

4. Chapel Hill

5. USA

Abstract

BLOCCs are readily assembled structures of laser cut acrylic and silicone, capable of imposing physiologically relevant oxygen gradients across 3D cell cultures. With sensors and cell-based readouts, we quantified cell-microenvironment relationships.

Funder

National Institute of General Medical Sciences

University of North Carolina

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AY/C9AY01690B

Reference37 articles.

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