A novel “AIE + ESIPT” near-infrared nanoprobe for the imaging of γ-glutamyl transpeptidase in living cells and the application in precision medicine

Author:

Liu Yi12345,Feng Bin12345,Cao Xiaozheng12345,Tang Gao12345,Liu Honglu6274,Chen Fang6274,Liu Meihui12345,Chen Qian8274,Yuan Kai6274,Gu Yonghong8274,Feng Xueping6274,Zeng Wenbin12345ORCID

Affiliation:

1. Xiangya School of Pharmaceutical Sciences

2. Central South University

3. Changsha 410013

4. PR China

5. The Molecular Imaging Research Center

6. Xiangya Hospital

7. Changsha

8. The Third Xiangya Hospital

Abstract

Novel near-infrared nanoprobe for detecting GGT in HepG2 cells and imaging in liver tumour tissue, satisfying for the need for clinical measure of GGT level.

Funder

National Natural Science Foundation of China

State Key Laboratory of Drug Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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