Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Author:

Anthis Alexandre H. C.12345,Tsolaki Elena6789,Didierlaurent Louis12345,Staubli Samuel12345,Zboray Robert1023115,Neels Antonia1023115ORCID,Dietrich Dörthe12131415,Manser Pius12345,Desbiolles Lotus May1617185,Leschka Sebastian1617185,Wildermuth Simon1617185,Lehner Sandro192345,Chavatte-Palmer Pascale2021222324,Jochum Wolfram2517185,Wick Peter12345ORCID,Dommann Alex12345,Bürki-Turnherr Tina12345ORCID,Fischer Tina2617185,Hornung René2617185,Bertazzo Sergio6789,Herrmann Inge K.12345ORCID

Affiliation:

1. Laboratory for Particles Biology Interactions

2. Department Materials Meet Life

3. Swiss Federal Laboratories for Materials Science and Technology (Empa)

4. CH-9014, St Gallen

5. Switzerland

6. Department of Medical Physics & Biomedical Engineering

7. University College London

8. London

9. UK

10. Center for X-ray Analytics

11. CH-8900, Dübendorf

12. Westfälische Wilhelms-Universität Münster

13. Institute of Inorganic and Analytical Chemistry

14. D-48149, Münster

15. Germany

16. Division of Radiology and Nuclear Medicine

17. Cantonal Hospital St Gallen (KSSG)

18. CH-9007, St Gallen

19. Laboratory for Advanced Fibers and Laboratory for Biointerfaces

20. UMR BDR

21. INRA

22. ENVA

23. Université Paris Saclay

24. F-78350, Jouy en Josas

25. Institute of Pathology

26. Department of Gynaecology

Abstract

This study reveals distinct characteristics of minerals formed during gestational ageing using nano-analytical characterization, and paves the way for the identification of markers for disease risks based on atypical placental mineral fingerprints.

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Schweizerische Herzstiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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