Regioselective access to di- and trisubstituted pyridines <i>via</i> a metal-oxidant-solvent-free domino reaction involving 3-chloropropiophenones-Reference-Cited by-同舟云学术

Regioselective access to di- and trisubstituted pyridines via a metal-oxidant-solvent-free domino reaction involving 3-chloropropiophenones

Published:2022 Issue:34 Volume:20 Page:6759-6765
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Patel Ashvani Kumar¹^ORCID,Rathor Shikha Singh¹,Samanta Sampak¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Indore, Simrol, 453552, India

Abstract

A metal-oxidant-solvent-free domino reaction of 3-chloropropiophenones, enolizable ketones and NH4OAc under an open atmosphere has been developed. This process generates a series of di- and trisubstituted pyridines regioselectively.

Funder

Science and Engineering Research Board

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01193J

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