Construction of a DNA walker nanomachine aptasensor for simultaneous detection of dual-cancer biomarkers

Author:

Tian Songbai12,Zheng Jiao13,Ji Xinghu3,Zhou Fuxiang1,He Zhike13ORCID

Affiliation:

1. Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Province Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University, 430071 Wuhan, China

2. School of Basic Medical Sciences, Hubei University of Medicine, 442000 Shiyan, China

3. College of Chemistry and Molecular Sciences, Wuhan University, 430072, P. R. China

Abstract

In this work, we introduce the operation of Exo I-powered DNA walker nanomachine for dual-biomarker simultaneous detection using a synchronous fluorescence strategy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

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