Ce6/Mn2+-chelated polydopamine@black-TiO2 nanoprobes for enhanced synergistic phototherapy and magnetic resonance imaging in 4T1 breast cancer

Author:

Gao Yang12345,Zhang Luyun12345,Liu Yanhong12345,Sun Sijia12345,Yin Zhibin12345,Zhang Lili678910,Li Aiguo678910,Lu Guangming1112131415ORCID,Wu Aiguo161718198ORCID,Zeng Leyong12345ORCID

Affiliation:

1. College of Chemistry & Environmental Science

2. Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education

3. Chemical Biology Key Laboratory of Hebei Province

4. Hebei University

5. Baoding 071002

6. Shanghai Synchrotron Radiation Facility

7. Shanghai Advanced Research Institute

8. Chinese Academy of Sciences

9. Shanghai 201204

10. P.R. China

11. Department of Medical Imaging

12. Jinling Hospital

13. School of Medicine

14. Nanjing University

15. Nanjing 210002

16. Cixi Institute of Biomedical Engineering

17. CAS Key Laboratory of Magnetic Materials and Devices

18. & Key Laboratory of Additive Manufacturing Materials of Zhejiang Province

19. Ningbo Institute of Materials Technology and Engineering

Abstract

Ce6/Mn2+-chelated, polydopamine (PDA)-coated black TiO2 (b-P25@PDA-Ce6 (Mn)) nanoprobes with core–shell structure were constructed for enhanced synergistic phototherapy and magnetic resonance (MR) imaging.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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