Radical cascade synthesis of γ-amino acids or γ-lactams <i>via</i> carboxyl-mediated intramolecular C

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Radical cascade synthesis of γ-amino acids or γ-lactams via carboxyl-mediated intramolecular C–H amination

Published:2024 Issue: Volume: Page:
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Huang Tao¹,Liu Can¹,Yuan Pan-Feng¹,Wang Tao¹,Yang Biao¹,Ma Yao¹,Liu Qiang¹^ORCID

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China

Abstract

A switchable chemo-divergent strategy for γ-amino acid and γ-lactam preparation via intramolecular γ C–H amination of carboxylic acids.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Gansu Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D4GC03057E

Reference63 articles.

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3. Biologically active γ-lactams: synthesis and natural sources

4. P. A.Sprengeler , S. H.Reich , J. T.Ernst , S. E.Webber , M.Shaggafi , D.Murphy and C.Tran , Effector Therapeutics, Inc., US, WO 2017/075394A1, 2017

5. X.Chen , D. R.Dragoli , J. F. J.Kallsiak , A.Krasinski , M. R.Leleti , V.Mali , J.Mcmahon , R.Singh , H.Tanaka , J.Yang , C.Yu and P.Zhang , Chemocentryx, Inc., US, US 2017/0144997A1, 2017

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