Darzens reaction of thioisatins and sulfonium salts: approach to the synthesis of thiochromenone derivatives with anticancer potency
Author:
Affiliation:
1. Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion
2. School of Chemistry & Chemical Engineering
3. Tianjin University of Technology
4. Tianjin 300384
5. P. R. China
6. Guilin Medical University
7. Guilin 541004
Abstract
A new Darzens reaction of thioisatins and sulfonium salts has, for the first time, been reported. Some of the synthesized thiochromenone derivatives have been found to show good potent anticancer activities against six different cancer cell lines.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Tianjin City
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00402A
Reference53 articles.
1. Copper-Catalyzed Domino Synthesis of 2-Arylthiochromanones through Concomitant C–S Bond Formations Using Xanthate as Sulfur Source
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