Mass spectrometry of modified RNAs: recent developments
Author:
Affiliation:
1. Rieveschl Laboratories for Mass Spectrometry
2. Department of Chemistry
3. University of Cincinnati
4. Cincinnati
5. USA
Abstract
A common feature of ribonucleic acids (RNAs) is that they can undergo a variety of chemical modifications, all of which can be detected by mass spectrometry. Here we highlight recent analytical developments in the field, which now enable quantitative characterization of complex mixtures of modified RNAs.
Funder
Defense Threat Reduction Agency
National Institutes of Health
Division of Chemistry
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/AN/C5AN01797A
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