Glycyrrhizic acid alters the hyperoxidative stress-induced differentiation commitment of MSCs by activating the Wnt/β-catenin pathway to prevent SONFH-Reference-Cited by-同舟云学术

Glycyrrhizic acid alters the hyperoxidative stress-induced differentiation commitment of MSCs by activating the Wnt/β-catenin pathway to prevent SONFH

Published:2023 Issue:2 Volume:14 Page:946-960
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Xu Huihui¹²^ORCID,Fang Liang¹²,Zeng Qinghe¹²,Chen Jiali¹²,Ling Houfu¹²,Xia Hanting¹²,Ge Qinwen¹²,Wu Congzi¹²,Zou Kaiao¹²,Wang Xu¹²,Wang Pinger¹²,Yuan Wenhua¹²,Dong Rui¹²³,Hu Songfeng⁴,Xiao Luwei¹²,He Bangjian³,Tong Peijian¹²³,Jin Hongting¹²³

Affiliation:

1. The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China

2. Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, Zhejiang, 310053, China

3. Department of Orthopaedic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310006, China

4. Department of Orthopaedics and Traumatology, Shaoxing Hospital of Traditional Chinese Medicine, Shaoxing, Zhejiang, 312000, China

Abstract

GA can reduce the level of OS induced by excessive GCs through the activation of the Wnt/β-catenin signaling pathway, thereby maintaining the osteolipogenic homeostasis of MSCs.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Chinese Medicine Research Program of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO02337G

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1. Resurfacing arthroplasty of the hip for avascular necrosis of the femoral head