Crystallisation and physicochemical property characterisation of conformationally-locked co-crystals of fenamic acid derivatives
Author:
Affiliation:
1. Department of Chemistry
2. University of Bath
3. Bath, UK
4. Engineering and Physical Sciences Research Council (EPSRC) Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC)
Abstract
Co-crystals of fenamic acid and its highly polymorphic derivatives with 4,4′-bipyridine are prepared using various crystallisation techniques and have been shown to afford single polymorphic forms for each of the co-crystals.
Funder
Engineering and Physical Sciences Research Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/CE/C5CE00297D
Reference37 articles.
1. Nonamorphism in Flufenamic Acid and a New Record for a Polymorphic Compound with Solved Structures
2. Conformational Polymorphism in a Non-steroidal Anti-inflammatory Drug, Mefenamic Acid
3. Mefenamic Acid Anti-Inflammatory Drug: Probing Its Polymorphs by Vibrational (IR and Raman) and Solid-State NMR Spectroscopies
4. Polymer-Induced Heteronucleation of Tolfenamic Acid: Structural Investigation of a Pentamorph
5. Pharmaceutical cocrystals and poorly soluble drugs
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