Impact of iron coordination isomerism on pyoverdine recognition by the FpvA membrane transporter of Pseudomonas aeruginosa
Author:
Affiliation:
1. Laboratoire de Glycochimie
2. des Antimicrobiens et des Agroressources
3. CNRS UMR7378/Université de Picardie Jules Verne
4. 80039 Amiens Cedex
5. France
Abstract
The chirality of Fe3+ binding by bacterial iron scavengers underpins their recognition by membrane transporters and could help design novel antibiotics.
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2017/CP/C7CP04529H
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3. Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics, World health organization technical report, 2017
4. Metal homeostasis and resistance in bacteria
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