Rice protein hydrolysates (RPHs) inhibit the LPS-stimulated inflammatory response and phagocytosis in RAW264.7 macrophages by regulating the NF-κB signaling pathway-Reference-Cited by-同舟云学术

Rice protein hydrolysates (RPHs) inhibit the LPS-stimulated inflammatory response and phagocytosis in RAW264.7 macrophages by regulating the NF-κB signaling pathway

Published:2016 Issue:75 Volume:6 Page:71295-71304
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wen Li¹²³⁴⁵,Chen Yuehua¹²³⁴⁵,Zhang Li⁶⁷⁸⁹¹⁰,Yu Huixin⁶⁷⁸⁹¹⁰,Xu Zhou¹²³⁴⁵,You Haixi¹²³⁴⁵,Cheng Yunhui¹²³⁴⁵

Affiliation:

1. Department of Food and Biological Engineering

2. College of Chemical and Biological Engineering

3. Changsha University of Science and Technology

4. Changsha 410114

5. China

6. Key Laboratory of Nuclear Medicine

7. Ministry of Health

8. Jiangsu Key Laboratory of Molecular Nuclear Medicine

9. Jiangsu Institute of Nuclear Medicine

10. Wuxi 214063

Abstract

Different RPH components inhibit LPS-induced NO and TNF-α production. RPHs-C-7-3 inhibits the expression of pro-inflammatory expression. RPHs-C-7-3 suppresses the LPS-stimulated phagocytic ability. RPHs-C-7-3 regulates the nuclear translocation of p65.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA08927E

Reference68 articles.

1. Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects

2. Milk proteins as a source of tryptophan-containing bioactive peptides

3. Peptides in pepsin–pancreatin hydrolysates from commercially available soy products that inhibit lipopolysaccharide-induced inflammation in macrophages