Kinetic resolution of sulfur-stereogenic sulfoximines by Pd(ii)–MPAA catalyzed C–H arylation and olefination-Reference-Cited by-同舟云学术

Kinetic resolution of sulfur-stereogenic sulfoximines by Pd(ii)–MPAA catalyzed C–H arylation and olefination

Published:2021 Issue:44 Volume:12 Page:14863-14870
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Mukherjee Kallol¹,Grimblat Nicolas²^ORCID,Sau Somratan¹,Ghosh Koushik¹,Shankar Majji¹,Gandon Vincent²³^ORCID,Sahoo Akhila K.¹^ORCID

Affiliation:

1. School of Chemistry, University of Hyderabad, Hyderabad, 500046, India

2. Nicolas Grimblat and Prof. Vincent Gandon, Institut de Chimie Moléculaire et des Matériaux d’Orsay, CNRS UMR 8182, Université Paris-Saclay, Bâtiment 420, 91405 Orsay Cedex, France

3. Laboratoire de Chimie Moléculaire (LCM), CNRS UMR 9168, Ecole Polytechnique, Institut Polytechnique de Paris, Route de Saclay, 91128 Palaiseau Cedex, France

Abstract

A Pd/MPAA catalysed KR of heteroaryl substituted sulfoximines through C–H alkenylation and arylation (up to >99% ee) is developed. In-depth DFT studies uncover the salient features.

Funder

University of Hyderabad

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC04299H

Reference51 articles.

1. Asymmetric C(sp2)H Activation

2. Recent development of direct asymmetric functionalization of inert C–H bonds