Gold-catalyzed <i>endo</i>-selective cyclization of alkynylcyclobutanecarboxamides: synthesis of cyclobutane-fused dihydropyridones-Reference-Cited by-同舟云学术

Gold-catalyzed endo-selective cyclization of alkynylcyclobutanecarboxamides: synthesis of cyclobutane-fused dihydropyridones

Published:2023 Issue:13 Volume:21 Page:2705-2708
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Garre M. Soledad¹^ORCID,Otárola Guillermo G.¹^ORCID,Merino Estíbaliz¹^ORCID,Sucunza David¹^ORCID,Aguilar Enrique²^ORCID,Quirós M. Teresa¹^ORCID,Vaquero Juan J.¹^ORCID,García-García Patricia¹^ORCID

Affiliation:

1. Universidad de Alcalá (IRYCIS), Departamento de Química Orgánica y Química Inorgánica, Instituto de Investigación Química “Andrés M. del Río” (IQAR), Campus Científico-Tecnológico, Facultad de Farmacia, Autovía A-II, Km 33.1, 28805-Alcalá de Henares, Madrid, Spain

2. Departamento de Química Orgánica e Inorgánica, Instituto Universitario de Química Organometálica “Enrique Moles”, Universidad de Oviedo, C/Julián Clavería, 8, 33006 Oviedo, Spain

Abstract

Gold-catalyzed cyclizations of alkynylcyclobutanes having an amide group proceed selectively through an endo-cyclization, providing an efficient methodology for the synthesis of cyclobutane-fused dihydropyridones.

Funder

Comunidad de Madrid

Universidad de Alcalá

Ministerio de Ciencia e Innovación

Ministerio de Economía y Competitividad

Instituto de Salud Carlos III

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00051F

Reference38 articles.

1. Homogeneous and Heterogeneous Gold Catalysis for Materials Science

2. Construction of Medium-Sized Rings by Gold Catalysis

3. Gold-Catalyzed Reactions of Specially Activated Alkynes, Allenes, and Alkenes

4. Gold-Catalyzed Conversion of Highly Strained Compounds

5. Gold-Catalyzed Synthesis of Small Rings