The protein-stabilizing effects of TMAO in aqueous and non-aqueous conditions-Reference-Cited by-同舟云学术

The protein-stabilizing effects of TMAO in aqueous and non-aqueous conditions

Published:2022 Issue:35 Volume:24 Page:21178-21187
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Monhemi Hassan¹²^ORCID,Hoang Hai Nam³⁴^ORCID,Standley Daron M.⁵,Matsuda Tomoko⁶^ORCID,Housaindokht Mohammad Reza²^ORCID

Affiliation:

1. Department of Chemistry, University of Neyshabur, Neyshabur, Iran

2. Research and Technology Center of Biomolecules, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran

3. Department of Food Technology, Faculty of Chemical Engineering, Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam

4. Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam

5. Laboratory of Systems Immunology, WPI Immunology Frontier Research Center Osaka University, Osaka 565–0871, Japan

6. School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan

Abstract

We present a new water-dependent molecular mechanism for the widely-used protein stabilizing osmolyte, trimethylamine N-oxide (TMAO), whose mode of action has remained controversial.

Funder

Iran National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CP/D2CP01279K

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