Near-infrared light-boosted antimicrobial activity of minocycline/hyaluronan/carbon nanohorn composite toward peri-implantitis treatments

Author:

Konishi Daisuke1,Hirata Eri1ORCID,Takano Yuta23ORCID,Maeda Yukari1,Ushijima Natsumi4,Yudasaka Masako56,Yokoyama Atsuro1

Affiliation:

1. Department of Oral Functional Prosthodontics, Faculty of Dental Medicine, Graduate school of Dental Medicine, Hokkaido University, Kita-13, Nishi-7, Sapporo 060-8586, Japan

2. Research Institute for Electronic Science, Hokkaido University, Kita-20, Nishi-10, Sapporo 001-0020, Japan

3. Graduate School of Environmental Science, Hokkaido University, Kita-10, Nishi-5, Sapporo 060-0810, Japan

4. Support Section for Education and Research, Faculty of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan

5. Nanomaterials Research Institute (NMRI), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan

6. Meijo University, Graduate School of Science and Technology, 1-501, Shiogamaguchi, Tenpaku, Nagoya 468-8502, Japan

Abstract

A near-infrared responsive composite material (MC/HA/CNH) was developed for the treatment of peri-implantitis. The MC/HA/CNH showed enhanced antimicrobial effect by near-infrared light irradiation, which lasted for 48 hours.

Funder

Japan Society for the Promotion of Science

Kao Foundation for Arts and Sciences

Publisher

Royal Society of Chemistry (RSC)

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