Impact of molecular rigidity on the gene delivery efficiency of core–shell tecto dendrimers

Author:

Wang Dayuan12345,Chen Liang12345,Gao Yue12345,Song Cong12345,Ouyang Zhijun12345,Li Changsheng12345,Mignani Serge678910,Majoral Jean-Pierre1112131415ORCID,Shi Xiangyang12345ORCID,Shen Mingwu12345ORCID

Affiliation:

1. State Key Laboratory for Modification of Chemical Fibers and Polymer Materials

2. Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine

3. College of Chemistry

4. Chemical Engineering and Biotechnology

5. Donghua University

6. CQM-Centro de Quimica da Madeira

7. Universidade da Madeira

8. Funchal 9020-105

9. Portugal

10. Université Paris Descartes

11. Laboratoire de Chimie de Coordination du CNRS

12. 205 route de Narbonne

13. Toulouse Cedex 4

14. France

15. Université Toulouse 118 route de Narbonne

Abstract

Core–shell tecto dendrimers with improved core rigidity can be synthesized using phosphorus dendrimers as cores for enhanced gene delivery applications.

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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