Diastereoselective synthesis of polycyclic indolinesviadearomative [4 + 2] cycloaddition of 3-nitroindoles withortho-aminophenylp-quinone methides-Reference-Cited by-同舟云学术

Diastereoselective synthesis of polycyclic indolinesviadearomative [4 + 2] cycloaddition of 3-nitroindoles withortho-aminophenylp-quinone methides

Published:2023 Issue:7 Volume:21 Page:1373-1378
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhou Shun¹²³,Qian Hui-Ling²,Zhao Jian-Qiang²^ORCID,You Yong²^ORCID,Wang Zhen-Hua²^ORCID,Yin Jun-Qing²,Zhang Yan-Ping²,Chen Ming-Feng⁴,Yuan Wei-Cheng¹²^ORCID

Affiliation:

1. National Engineering Research Center of Chiral Drugs, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China

2. Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China

3. University of Chinese Academy of Sciences, Beijing, 100049, China

4. Zhejiang Nexchem Pharmaceutical Co., Ltd., Jinhua, 321016, China

Abstract

The first dearomative [4 + 2] cycloaddition of 3-nitroindoles withortho-aminophenylp-QMs was developed, affording a series of structurally diverse tetrahydro-5H-indolo[2,3-b]quinolones with good results.

Funder

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Chengdu University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB02303B

Reference50 articles.

1. Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids