Important cytotoxic and cytostatic effects of new copper(i)–phosphane compounds with N,N, N,O and N,S bidentate ligands-Reference-Cited by-同舟云学术

Important cytotoxic and cytostatic effects of new copper(i)–phosphane compounds with N,N, N,O and N,S bidentate ligands

Published:2018 Issue:23 Volume:47 Page:7819-7829
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Morais Tânia S.¹²³⁴⁵^ORCID,Jousseaume Yann¹²³⁴⁵,M. Piedade M. Fátima⁵²³⁴¹,Roma-Rodrigues Catarina⁶⁷⁸⁹⁴,Fernandes Alexandra R.⁶⁷⁸⁹⁴,Marques Fernanda¹⁰¹¹³⁴^ORCID,Villa de Brito Maria J.¹²³⁴⁵,Garcia M. Helena¹²³⁴⁵

Affiliation:

1. Centro de Química Estrutural

2. Faculdade de Ciências

3. Universidade de Lisboa

4. Portugal

5. Departamento de Química e Bioquímica

6. UCBIO

7. Departamento de Ciências da Vida

8. Faculdade de Ciências e Tecnologia

9. Universidade Nova de Lisboa

10. Centro de Ciências e Tecnologias Nucleares

11. Instituto Superior Técnico

Abstract

Synthesis of new phosphane–Cu(i) complexes with bidentate ligands displaying cytotoxic and cytostatic effects that make them attractive as anticancer agents.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/DT/C8DT01653D

Reference42 articles.

1. Copper storage diseases: Menkes, Wilson's, and Cancer

2. Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics

3. The many “faces” of copper in medicine and treatment

4. Bioinorganic aspects of angiogenesis

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