Identification of chemical components and rat serum metabolites in Danggui Buxue decoction based on UPLC-Q-TOF-MS, the UNIFI platform and molecular networks-Reference-Cited by-同舟云学术

Identification of chemical components and rat serum metabolites in Danggui Buxue decoction based on UPLC-Q-TOF-MS, the UNIFI platform and molecular networks

Published:2023 Issue:46 Volume:13 Page:32778-32785
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lv Yanhui¹²,Xu Xike¹,Yang Jishun³,Gao Yuan¹²,Xin Jiayun¹²,Chen Wei¹^ORCID,Zhang Li²,Li Jiali²,Wang Jie²,Wei Yanping²,Wei Xintong²,He Jixiang²,Zu Xianpeng¹^ORCID

Affiliation:

1. Department of Natural Medicinal Chemistry, School of Pharmacy, Naval Medical University, Shanghai 200433, China

2. Department of Pharmaceutical Analysis, School of Pharmacy, School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China

3. Medical Security Center, Naval Medical Center, Naval Medical University, Shanghai 200433, China

Abstract

The material basis of DBD was annotated using UPLC-Q-TOF-MS, UNIFI platform and molecular network. 207 chemical components were unambiguously or tentatively identified in DBD. A total of 29 prototypical constituents and 51 metabolites were identified in the serum of rats after DBD administration.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Shanghai Municipal Health Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA04419J

Reference37 articles.

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2. Chemical profiling of Fufang-Xialian-Capsule by UHPLC-Q-TOF-MS and its antioxidant activity evaluated by in vitro method

3. Identification and characterization of chemical constituents in Dengzhan Shengmai Capsule and their metabolites in rat plasma by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

4. Characterization and Discrimination of Ophiopogonis Radix with Different Levels of Sulfur Fumigation Based on UPLC-QTOF-MS Combined Molecular Networking with Multivariate Statistical Analysis

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