Synthesis and biological evaluation of natural <i>Lachnophyllum</i> methyl ester, <i>Lachnophyllum</i> lactone and their synthetic analogs-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of natural Lachnophyllum methyl ester, Lachnophyllum lactone and their synthetic analogs

Published:2024 Issue: Volume: Page:
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Adande Kodjo¹²,Simalou Oudjaniyobi²^ORCID,Ardanuy Juline¹,Eloh Kodjo³,Mehalla Chérine⁴,Constant Patricia⁴^ORCID,Fabing Isabelle¹^ORCID,Génisson Yves¹^ORCID,Ballereau Stéphanie¹^ORCID

Affiliation:

1. Laboratoire de Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (SPCMIB), Université de Toulouse, CNRS, Université Toulouse III – Paul Sabatier (UT3), 118 route de Narbonne, 31062, Toulouse Cedex 9, France

2. Laboratoire de Chimie Organique et Des Substances Naturelles (Lab COSNat), Département de Chimie, Faculté Des Sciences, Université de Lomé, Lomé, Togo

3. Laboratoire de Chimie Organique et des Sciences de l'Environnement (LaCOSE), Département de Chimie, Faculté Des Sciences et Techniques, Université de Kara, Kara, Togo

4. Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France

Abstract

Synthesis of natural (2Z)-Lachnophyllum methyl ester and (4Z)-Lachnophyllum lactone is reported. The developed routes enabled the first synthesis of non-natural analogs of these natural compounds. Biological activities of the series were evaluated.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB01224K

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