Synthesis, conformational properties, and molecular recognition abilities of novel prism[5]arenes with branched and bulky alkyl groups

Author:

Del Regno Rocco1ORCID,Della Sala Paolo1ORCID,Vollono Ivan1ORCID,Talotta Carmen1ORCID,Neri Placido1ORCID,Hickey Neal2ORCID,Joshi Siddharth2ORCID,Geremia Silvano2ORCID,Gaeta Carmine1ORCID

Affiliation:

1. Dipartimento di Chimica e Biologia “A. Zambelli”. Università di Salerno, Via Giovanni Paolo II, I-84084, Fisciano, Salerno, Italy

2. Centro di Eccellenza in Biocristallografia, Dipartimento di Scienze Chimiche e Farmaceutiche, Università di Trieste, Via L. Giorgieri 1, I-34127, Trieste, Italy

Abstract

The direct macrocyclization to prism[5]arenes of 2,6-dialkoxynaphthalenes with branched and bulky alkyl groups has been obtained in good yields. The chirality of these novel prism[5]arenes is stable on the NMR time scale.

Funder

Ministero dell'Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

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