Complexes of Zn(ii) with a mixed tryptanthrin derivative and curcumin chelating ligands as new promising anticancer agents

Author:

Wang Zhen-Feng12,Nong Qun-Xue3,Yu Hua-Lian3,Qin Qi-Pin34ORCID,Pan Feng-Hua3,Tan Ming-Xiong3ORCID,Liang Hong4,Zhang Shu-Hua12ORCID

Affiliation:

1. Guangxi Key Laboratory of Electrochemical and Magnetochemical Functional Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, P. R. China

2. College of Chemistry, Guangdong University of Petrochemical Technology, Maoming, Guangdong, 525000, P. R. China

3. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, College of Chemistry and Food Science, Yulin Normal University, 1303 Jiaoyudong Road, Yulin 537000, PR China

4. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmacy, Guangxi Normal University, 15 Yucai Road, Guilin 541004, PR China

Abstract

A facile strategy toward the synthesis of theranostic curcumin–tryptanthrin–Zn(ii) complexes for cancer-specific therapy is demonstrated.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Province

Collaborative Innovation Center for Exploration of Hidden Nonferrous Metal Deposits and Development of New Materials in Guangxi

Guangdong University of Petrochemical Technology

Yulin Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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