Visible light-enabled synthesis of phosphorylated indolizine and pyridoindole derivatives <i>via</i> HAT-mediated radical cascade cyclization-Reference-Cited by-同舟云学术

Visible light-enabled synthesis of phosphorylated indolizine and pyridoindole derivatives via HAT-mediated radical cascade cyclization

Published:2023 Issue:47 Volume:21 Page:9341-9345
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Shen Kunrong¹,Feng Chuan¹,Liu Yilei¹,Yi Dong¹^ORCID,Lin Peng¹,Li Huifang¹,Gong Yimou¹,Wei Siping¹^ORCID,Fu Qiang¹^ORCID,Zhang Zhijie¹²^ORCID

Affiliation:

1. Green Pharmaceutical Technology Key Laboratory of Luzhou City, Central Nervous System Drug Key Laboratory of Sichuan Province, School of Pharmacy, Southwest Medical University, Luzhou, 646000, China

2. State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou, 350116, China

Abstract

Phosphinoyl radicals were generated from H-phosphonates via a photocatalytic HAT process and applied to the construction of phosphorylated heterocycles under metal-free conditions.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Sichuan Province

Southwest Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01675G

Reference40 articles.

1. Highly Diastereoselective Multicomponent Synthesis of Spirocyclopropyl Oxindoles Enabled by Rare-Earth Metal Salts

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4. Synthesis, Oral Bioavailability Determination, and in vitro Evaluation of Prodrugs of the Antiviral Agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)

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