Mitochondria-targeting biocompatible fluorescent BODIPY probes-Reference-Cited by-同舟云学术

Mitochondria-targeting biocompatible fluorescent BODIPY probes

Published:2024 Issue:13 Volume:15 Page:4846-4852
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Walter Edward R. H.¹²^ORCID,Lee Lawrence Cho-Cheung²³^ORCID,Leung Peter Kam-Keung³⁴^ORCID,Lo Kenneth Kam-Wing³⁴^ORCID,Long Nicholas J.¹^ORCID

Affiliation:

1. Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, W12 0BZ, UK

2. Laboratory for Synthetic Chemistry and Chemical Biology Limited, Units 1503-1511, 15/F, Building 17 W, Hong Kong Science Park, New Territories, Hong Kong, P. R. China

3. Department of Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, P. R. China

4. State Key Laboratory of Terahertz and Millimetre Waves, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, P. R. China

Abstract

Biocompatible fluorescent BODIPY probes with excellent quantum yields, demonstrating a high mitochondrial membrane potential (MMP)-sensitive localisation in the mitochondria. PEGylation improved biocompatibility and lowers cytotoxicity.

Funder

Innovation and Technology Commission - Hong Kong

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D3SC06445J

Reference41 articles.

1. Mitochondrial membrane potential

2. The multifaceted contributions of mitochondria to cellular metabolism

3. Mechanisms of Mitochondrial Dysfunction in Alzheimer’s Disease

4. The Mitochondrial Basis of Aging

5. Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications

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