Binding motif of ebselen in solution: chalcogen and hydrogen bonds team up

Author:

Daolio Andrea12345ORCID,Scilabra Patrick12345ORCID,Di Pietro Maria Enrica12345ORCID,Resnati Chiara6785ORCID,Rissanen Kari9101112ORCID,Resnati Giuseppe12345ORCID

Affiliation:

1. Department of Chemistry

2. Materials

3. Chemical Engineering “Giulio Natta”

4. Milano I-20131

5. Italy

6. Recidency Program Clinical Pharmacology & Toxicology

7. Università degli Studi della Campania “Luigi Vanvitelli”

8. Napoli I-80138

9. Department Chemistry

10. University of Jyväskylä

11. Jyväskylä

12. Finland

Abstract

Ebselen, a compound active against SARS-CoV-2, forms a bifurcated supramolecular synthon thanks to chalcogen bond and hydrogen bond cooperation.

Funder

Fondazione Cariplo

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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