Straightforward chemo- and stereoselective fluorocyclopropanation of allylic alcohols: exploiting the electrophilic nature of the not so elusive fluoroiodomethyllithium

Author:

Colella Marco1234,Tota Arianna1234,Großjohann Angela1234,Carlucci Claudia1234,Aramini Andrea564,Sheikh Nadeem S.78910,Degennaro Leonardo1234,Luisi Renzo1234ORCID

Affiliation:

1. Department of Pharmacy – Drug Sciences

2. University of Bari

3. 70125 Bari

4. Italy

5. Department of Discovery Dompé Farmaceutici S.p.A.

6. L’Aquila 67100

7. Department of Chemistry

8. College of Science, King Faisal University

9. Al-Ahsa 31982

10. Saudi Arabia

Abstract

The not so elusive carbenoid fluoroiodomethyllithium disclosed its electrophilic nature in an unprecedented direct and stereoselective fluorocyclopropanation of allylic alcohols.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Ministero dello Sviluppo Economico

Deanship of Scientific Research, King Faisal University

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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