Cinnamaldehyde protects against ligature-induced periodontitis through the inhibition of microbial accumulation and inflammatory responses of host immune cells

Author:

Ou Yanjing1,Yan Mingdong2,Gao Guanglin2,Wang Wenjie2,Lu Qiaoqiao1,Chen Jiang1ORCID

Affiliation:

1. Fujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, Fujian, 350002, PR China

2. Institute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, Fujian, 350002, PR China

Abstract

Cinnamaldehyde inhibited periodontitis in mice by suppressing microbial accumulation and the P. gingivalis-induced inflammatory responses of macrophages and PDLCs, and may help in tissue repair by anti-senescence and osteogenic induction.

Funder

National Natural Science Foundation of China

Distinguished Young Scientific Research Talents Plan in Universities of Fujian Province

Fujian Provincial Health Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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