Sustained delivery of anti-VEGFs from thermogel depots inhibits angiogenesis without the need for multiple injections-Reference-Cited by-同舟云学术

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Sustained delivery of anti-VEGFs from thermogel depots inhibits angiogenesis without the need for multiple injections

Published:2019 Issue:11 Volume:7 Page:4603-4614
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Xue Kun¹²³⁴⁵,Zhao Xinxin⁶²³⁷⁵,Zhang Zhongxing¹²³⁴⁵,Qiu Beiying⁶²³⁷⁵,Tan Queenie Shu Woon⁶²³⁷⁵,Ong Kok Haur⁶²³⁷⁵,Liu Zengping⁸⁹¹⁰¹¹¹²^ORCID,Parikh Bhav Harshad⁶²³⁷⁵,Barathi Veluchamy Amutha⁸⁹¹⁰¹¹¹²^ORCID,Yu Weimiao⁶²³⁷⁵,Wang Xiaomeng⁶²³⁷⁵,Lingam Gopal⁸⁹¹⁰¹¹^ORCID,Hunziker Walter⁶²³⁷⁵^ORCID,Su Xinyi⁶²³⁷⁵^ORCID,Loh Xian Jun¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Materials Research and Engineering (IMRE)

2. Agency for Science

3. Technology and Research (A*STAR)

4. Singapore 138634

5. Singapore

6. Institute of Molecular and Cell Biology (IMCB)

7. Singapore 138673

8. Department of Ophthalmology

9. Yong Loo Lin School of Medicine

10. National

11. Singapore 119228

12. Singapore Eye Research Institute

Abstract

Polyurethane thermogels show sustained delivery of bioactive anti-VEGFs therapeutics to the eye.

Funder

Agency for Science, Technology and Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/BM/C9BM01049A

Reference74 articles.

1. Vascular endothelial growth factor in eye disease

2. Ocular delivery of proteins and peptides: Challenges and novel formulation approaches

3. Challenges and obstacles of ocular pharmacokinetics and drug delivery

4. Delivery strategies for treatment of age-related ocular diseases: From a biological understanding to biomaterial solutions

5. SYSTEMIC PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVITREAL AFLIBERCEPT, BEVACIZUMAB, AND RANIBIZUMAB

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