Development of boronic acid catalysts for direct amidation of aromatic carboxylic acids using fluorescence-based screening-Reference-Cited by-同舟云学术

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Development of boronic acid catalysts for direct amidation of aromatic carboxylic acids using fluorescence-based screening

Published:2024 Issue:30 Volume:22 Page:6103-6107
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ryoo Jeong Yup¹,Han Min Su¹^ORCID

Affiliation:

1. Department of Chemistry, Gwangju Institute of Science and Technology (GIST), 123, Cheomdangwagi-ro, Buk-gu, Gwangju, 61005, Republic of Korea

Abstract

Boronic acid catalysts for direct amidation were rapidly evaluated using fluorescence-based screening, achieving yields up to 98% with the most effective catalyst among them.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00576G

Reference58 articles.

1. Analysis of the reactions used for the preparation of drug candidate molecules

2. Rethinking amide bond synthesis

3. Amides in Nature and Biocatalysis

4. A green chemistry perspective on catalytic amide bond formation

5. Efficient and accessible silane-mediated direct amide coupling of carboxylic acids and amines

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