Ion release behavior of vanadium-doped mesoporous bioactive glass particles and the effect of the released ions on osteogenic differentiation of BMSCs via the FAK/MAPK signaling pathway-Reference-Cited by-同舟云学术

Ion release behavior of vanadium-doped mesoporous bioactive glass particles and the effect of the released ions on osteogenic differentiation of BMSCs via the FAK/MAPK signaling pathway

Published:2021 Issue:37 Volume:9 Page:7848-7865
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Li Jiangfeng¹,Li Junying¹,Wei Yuhao²,Xu Na¹,Li Jingtao²,Pu Ximing¹^ORCID,Wang Juan¹,Huang Zhongbing¹^ORCID,Liao Xiaoming¹,Yin Guangfu¹^ORCID

Affiliation:

1. College of Biomedical Engineering, Sichuan University, No. 24, South 1st Section, 1st Ring Road, Chengdu, 610065, P. R. China

2. Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China

Abstract

V(v) ions released from V-MBG promote osteogenic differentiation of rBMSCs via FAK/MAPK (pERK1/2) signaling pathway in combination with the synergistic effect of Si, Ca, P ions, and V-MBG promote new bone formation in the cranial defect of rats.

Funder

National Key Research and Development Program of China

Key Research and Development Program of Sichuan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB01479J

Reference79 articles.

1. Fracture healing under healthy and inflammatory conditions

2. Localized delivery of growth factors for angiogenesis and bone formation in tissue engineering