An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels-Reference-Cited by-同舟云学术

An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels

Published:2021 Issue:52 Volume:11 Page:32824-32829
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Salari Alinaghi¹²^ORCID,Appak-Baskoy Sila¹³^ORCID,Coe Imogen R.¹³⁴,Tsai Scott S. H.¹⁵^ORCID,Kolios Michael C.¹⁶^ORCID

Affiliation:

1. Institute for Biomedical Engineering, Science and Technology (iBEST), Toronto, ON M5B 1T8, Canada

2. Biomedical Engineering Graduate Program, Ryerson University, Toronto, ON M5B 2K3, Canada

3. Department of Chemistry and Biology, Ryerson University, Toronto, ON M5B 2K3, Canada

4. Molecular Science Graduate Program, Ryerson University, Toronto, ON M5B2K3, Canada

5. Department of Mechanical and Industrial Engineering, Ryerson University, Toronto, ON M5B 2K3, Canada

6. Department of Physics, Ryerson University, Toronto, ON M5B 2K3, Canada

Abstract

We report a novel acoustofluidic method for detaching adhered cells from microchannel surfaces. This method enables a rapid (i.e., on the order of seconds), cost-effective, and easy-to-operate cell detachment strategy with high cellular viability.

Funder

Canada Foundation for Innovation

Ryerson University

Natural Sciences and Engineering Research Council of Canada

Ontario Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA04875A

Reference35 articles.

1. Ueber das Trypsin (Enzym des Pankreas)

2. Cell Coat in Tumor Cells – Effects of Trypsin and EDTA: A Biochemical and Morphological Study

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