Natural compounds from Juncus plants interacting with telomeric and oncogene G-quadruplex structures as potential anticancer agents-Reference-Cited by-同舟云学术

Natural compounds from Juncus plants interacting with telomeric and oncogene G-quadruplex structures as potential anticancer agents

Published:2021 Issue:45 Volume:19 Page:9953-9965
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Platella Chiara¹,Capasso Domenica²³,Riccardi Claudia¹^ORCID,Musumeci Domenica¹⁴,DellaGreca Marina¹^ORCID,Montesarchio Daniela¹^ORCID

Affiliation:

1. Department of Chemical Sciences, University of Naples Federico II, via Cintia, 21, 80126 Naples, Italy

2. CIRPEB, University of Naples Federico II, Naples, Italy

3. CESTEV, University of Naples Federico II, Naples, Italy

4. Institute of Biostructures and Bioimaging (IBB) – CNR, Naples, Italy

Abstract

One dihydrodibenzoxepin from Juncus plants proved to selectively interact with telomeric and oncogene G-quadruplexes by targeting their grooves. It showed anticancer activity on leukemia cells together with low-to-null effects on normal cells.

Funder

Associazione Italiana per la Ricerca sul Cancro

Fondazione Umberto Veronesi

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01995C

Reference52 articles.

1. HELIX FORMATION BY GUANYLIC ACID

2. Quadruplex Nucleic Acids as Novel Therapeutic Targets

3. The story of quadruplex DNA – it started with a Bang!

4. The application of DNA and RNA G-quadruplexes to therapeutic medicines

5. The regulation and functions of DNA and RNA G-quadruplexes

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Modular symmetric ligands for selective recognition of cancer-relevant G-quadruplexes;Journal of Molecular Structure;2024-03

2. Acetate/Alkoxide/Halide Shuttle Systems Mediated by Lewis Acid Catalysts for Insertion Reaction of a One-Carbon Unit into Carbon–Carbon or Carbon–Halogen Bonds;Synlett;2023-07-24

3. Exploring the Binding of Natural Compounds to Cancer-Related G-Quadruplex Structures: From 9,10-Dihydrophenanthrenes to Their Dimeric and Glucoside Derivatives;International Journal of Molecular Sciences;2023-04-24

4. Binding mechanism of andrographolide with intramolecular antiparallel G-quadruplexes of therapeutic importance: an in-silico analysis;Molecular Simulation;2023-03-29

5. Selective Targeting of Cancer-Related G-Quadruplex Structures by the Natural Compound Dicentrine;International Journal of Molecular Sciences;2023-02-17