Unexpected insights into antibacterial activity of zinc oxide nanoparticles against methicillin resistantStaphylococcus aureus(MRSA)
Author:
Affiliation:
1. Department of Emergency Medicine
2. University of Michigan
3. Ann Arbor
4. USA
5. Biointerfaces Institute University of Michigan
6. Department of Chemical Engineering
7. Department of Biomedical Engineering
Abstract
Zinc oxide nanoparticles cause marked up-regulation of pyrimidine biosynthesis and sugar metabolism but consistent down-regulation of amino acid synthesis in MRSA, suggesting a previously unrecognized mechanism of action.
Funder
National Science Foundation
National Institute of Allergy and Infectious Diseases
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NR/C7NR08499D
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