Coiled coils 9-to-5: rational de novo design of α-helical barrels with tunable oligomeric states-Reference-Cited by-同舟云学术

Coiled coils 9-to-5: rational de novo design of α-helical barrels with tunable oligomeric states

Author:

Dawson William M.¹^ORCID,Martin Freddie J. O.¹,Rhys Guto G.¹²^ORCID,Shelley Kathryn L.¹³^ORCID,Brady R. Leo³^ORCID,Woolfson Derek N.¹³⁴^ORCID

Affiliation:

1. School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK

2. Department of Chemistry, University of Bayreuth, Universitätsstraße 30, 95447 Bayreuth, Germany

3. School of Biochemistry, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK

4. Bristol BioDesign Institute, University of Bristol, Life Sciences Building, Tyndall Avenue, Bristol BS8 1TQ, UK

Abstract

Systematic de novo design of peptides that form α-helical barrels with functionalisable central channels with a range of internal diameters.

Funder

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

Reference41 articles.

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