Oxidation of amine α-carbon to amide: a review on direct methods to access the amide functionality

Author:

Nagaraaj P.1234ORCID,Vijayakumar V.1234

Affiliation:

1. Department of Chemistry

2. Anna University

3. Chennai-25

4. India

Abstract

A number of methods have been adopted for the synthesis of amides; among these methods, the oxidation of an amine to an amide is growing in interest as a means to prepare this imperative functional group.

Funder

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference182 articles.

1. Amide bond formation: beyond the myth of coupling reagents

2. A. Greenberg , C. M.Breneman and J. F.Liebman , The Amide Linkage: Structural Significance in Chemistry, Biochemistry, and Materials Science , Wiley , New York , 2000

3. C. A. G. N. Montalbetti and V. M.Falque , Synthetic Chemistry: Formation of the Amide Bond , Wiley Encyclopedia of Chemical Biology , 2008 , pp. 1–17

4. Rethinking amide bond synthesis

5. Metal-catalysed approaches to amide bond formation

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