Inhibitory effects of Centella asiatica (L.) Urban on enlarged prostate through androgen receptor and PI3K/Akt signaling pathways

Author:

Choi Young-Jin123,Fan Meiqi4,Wedamulla Nishala Erandi1235,Tang Yujiao6,Bae Sung Mun7,Hwang Ji-Young8,Kim Eun-Kyung1239ORCID

Affiliation:

1. Department of Food Science and Nutrition, Dong-A University, Busan 49315, Republic of Korea

2. Center for Silver-targeted Biomaterials, Brain Busan 21 Plus Program, Dong-A University, Busan 49315, Republic of Korea

3. Department of Health Sciences, the Graduate School of Dong-A University, Busan 49315, Republic of Korea

4. Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju 27478, Republic of Korea

5. Department of Export Agriculture, Faculty of Animal Science and Export Agriculture, Uva Wellassa University, Badulla 90000, Sri Lanka

6. School of Bio-Science and Food Engineering, Changchun University of Science and Technology, Changchun 130600, China

7. Gyeongnam Agricultural Research and Extension Services, Jinju 52733, Korea

8. Department of Food Science & Technology, Dong-Eui University, Busan 47340, Korea

9. Center for Food & Bio Innovation, Dong-A University, Busan 49315, Korea

Abstract

CAA inhibits prostate cell proliferation in BPH by inhibiting androgen receptor signaling and the PI3K/Akt pathway.

Funder

National Research Foundation of Korea

Rural Development Administration

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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