Advances in targeting the folate receptor in the treatment/imaging of cancers
Author:
Affiliation:
1. Department of Chemistry
2. University College London
3. London
4. UK
5. Research Institute for Medicines (iMed.ULisboa)
Abstract
The folate receptor (FR) is an important biomarker for many cancers, and its overexpression on tumours can be exploited for targeted therapy, diagnosis and imaging.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/SC/C7SC04004K
Reference105 articles.
1. Design, synthesis and biological evaluation of a highly-potent and cancer cell selective folate–taxoid conjugate
2. A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors
3. Targeted delivery for regenerative medicines: an untapped opportunity for drug conjugates
4. Prostate-Specific Membrane Antigen Targeted Imaging and Therapy of Prostate Cancer Using a PSMA Inhibitor as a Homing Ligand
5. An Activatable Theranostic for Targeted Cancer Therapy and Imaging
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